The strongest reasons to stay here include Prime location → all major attractions nearby, Excellent transport connectivity, Huge choice of stays, restaurants, and bars. These factors typically matter most for first-time visitors who want to reduce friction between the station, stay, and main sightseeing areas. They can also make the district easier to recommend when the goal is a simple stay rather than a very specific niche such as nightlife or the lowest possible room price.
The main trade-offs are Higher crime than most districts in Berlin, Pickpocketing, scams, and street issues (especially Alexanderplatz), Crowded and chaotic. These are not always deal-breakers, but they are exactly the details that can turn a cheap booking into a frustrating stay. Treat them as prompts for checking the exact street, nearest transit stop, and recent recent reviews.